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From114US$ /night
Check-in
28Jun2025Select date
Check-out
29Jun2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

2516 Guess Road, Durham, North Carolina, United States, 27705

Rooms & Amenities

The Holiday Inn Express Durham offers newly renovated guest rooms with free Wi-Fi, 37-inch flat-screen TVs, microwaves, and refrigerators. Select rooms include upgraded amenities like extended desks and additional storage. All rooms feature laptop-friendly workspaces, air conditioning, and triple-sheeted bedding. Accessible rooms have bathtubs, grab bars, and roll-in showers.

Dining & Breakfast

Guests enjoy a complimentary Express Start Breakfast with hot and cold options. Coffee and tea are available in the lobby. Nearby dining includes Texas Roadhouse for steaks and ribs, Randy's Pizza for NY-style pies, and Hog Heaven for award-winning barbecue.

Leisure & Fitness

The hotel has a seasonal outdoor pool open from May to September and a fitness center with free weights and machines. Duke University's campus, featuring Duke Chapel and the Sarah P. Duke Gardens, is a short drive away. The Durham Performing Arts Center hosts concerts and Broadway shows.

Location & Transport

The hotel is three miles from the Durham Bulls Athletic Park and two miles from Northgate Mall. Duke University, the NC Museum of Life and Science, and downtown Durham's Tobacco District are within minutes. Complimentary self-parking is available on-site, with wheelchair-accessible spaces near all entrances.

Services & Accessibility

The hotel provides a business center with printing and scanning services, free Wi-Fi, and a medical shuttle (Mon-Fri). Accessible features include ADA-compliant elevators, Braille signage, and wheelchair-friendly routes. Pets are welcome for a one-time fee, and late check-out is available upon request.

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Choose the Room

From cozy doubles to spacious family suites – all with flexible options, breakfast, and exclusive deals.
Standard Room
Max:
2 persons
325 sq. feet 
Bed options:
2 Double beds
Shower
Coffee machine
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Standard Queen Room Two Queen Beds
Max:
4 persons
325 sq. feet 
Bed options:
2 King Size Beds
Shower
Coffee machine
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Standard King Room
Max:
2 persons
325 sq. feet 
Bed options:
1 King-size bed
Shower
Coffee machine
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Check Dates & Room Rates

See what's available for your travel dates

Getting around

All Transportation Options at a Glance

City Centre
Durham 2.7 mi
Airports
Raleigh-Durham International (RDU) 16.8 mi
Danville Regional (DAN) 55.3 mi

Amenities

Thoughtfully designed amenities for a comfortable & memorable stay

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Lift
  • Coffee shop
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre

Services

  • Housekeeping
  • Shops/Commercial services

Business

  • Business centre
  • Fax/Photocopying

Children

  • Children's buffet

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Saltwater pool
  • Seasonal outdoor pool
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
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Location

2516 Guess Road, Durham, North Carolina, United States, 27705
Map view
2516 Guess Road, Durham, North Carolina, United States, 27705
Nearby
Faith in Christ Church
1400 ft
Restaurants
Hog Heaven Bar-B-Q
500 ft
2419 Guess Rd
Pad Thai
600 ft
2425 Guess Rd
Ihop
3200 ft
1821 N Pointe Dr
The French Corner Bakery
2000 ft
2005 N Pointe Dr Ste B
McDonald's
1500 ft
2700 Guess Rd
Popeyes Louisiana Kitchen
1800 ft
2723 Guess Road
Jimmy's Famous Hot Dogs
2000 ft
2728 Guess Rd
Bojangles' Famous Chicken 'n Biscuits
2100 ft
2801 Guess Rd.
Rudino's Pizza & Grinders
3600 ft
1515 N Pointe Dr
La Cacerola Cafe and Restaurant
2600 ft
2016 Guess Rd
The Dog House
2600 ft
2009 Guess Rd

Guest Ratings & Reviews

Real Guest Experiences & Ratings
84%
enjoyed their stay & would return
8.4/10
Great
Rooms
8.3
Location
7.7
Service
9.0
Dining
7.3
Guest reviews
8.4/10
based on 3 reviews
8.7
8.7/10 based on 185 reviews
Jon
United States, February  2024
7.6/10

The hotel was clean and spacious, making it very comfortable overall. However, noise from heavy traffic on a secondary road starting early in the morning was a downside.

Rooms
8.0
The rooms were clean, spacious, and comfortable.
Service
9.0
The staff was very polite, helpful, and friendly, although they were unsure about quieter room options. The service was excellent, with courteous and professional interactions. The hotel was clean and had a variety at the breakfast bar.
Location
7.0
The location was nice despite being in a congested area due to heavy traffic. The breakfast buffet was surprisingly clean, although guest congestion and messiness were noticeable.
Dining
6.0
The dining experience improved after voicing concerns, but initially, it was subpar. The variety was good eventually, but not impressive at first.
Facilities
The facilities were adequate, with no specific positives or negatives highlighted.
Alexander
United States, August  2023
9.0/10

My stay at the hotel was truly enjoyable. The rooms were very clean and comfortable, providing a cozy retreat upon returning at three in the afternoon. The service was top-notch, with the staff being super friendly and helpful. The location was perfect for a campus visit to Duke University, offering easy access to the city. The dining experience was very well done, with a variety of choices to satisfy different preferences.

Rooms
9.0
The rooms were very clean and comfortable, offering a super clean environment.
Service
9.0
The service was awesome, very friendly, courteous, and professional.
Location
9.0
The location was perfect for a campus visit to Duke University, with easy access to the city.
Dining
9.0
The dining experience was very well done and also kept clean, offering a variety of choices.
Facilities
The hotel facilities were very accommodating and convenient for a pleasant stay.
Eric
United States, July  2023
7.8/10

My stay at the hotel was quite pleasant. The rooms were clean and comfortable, and the staff was very friendly. However, the dining experience left room for improvement with limited breakfast options. The location was convenient, but there were some issues with guest congestion at the breakfast bar. Overall, a good value for the money.

Rooms
8.0
The room was clean and comfortable with a mini fridge, microwave, and coffee maker.
Service
9.0
The staff took good care of us during our stay and were helpful and friendly.
Location
7.0
The hotel's location was perfect for our visit to Duke University, but the area was congestive due to heavy traffic.
Dining
7.0
The dining experience was nice, but there were some issues after we voiced our concerns.
Facilities
8.0
The facilities were well done and kept clean.
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Check-in
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Rooms and Guests2 Guests, 1 Room